UPB
Upstream Bio, Inc.
NasdaqGS Healthcare United States
4,85 $US
-3.77% today
-82.08% YTD · -74.43% 1Y
5
Insider transactions
SEC Form 4 · AMF · BaFin — rolling 90 days
15
Hedge funds tracked
Latest available SEC 13F filings
51
/ 100
MIXED

Analysis Upstream Bio, Inc. (UPB) — Kairos Score 51/100

Composite score aggregating 8 smart money dimensions: insiders (SEC/AMF/BaFin), hedge funds, politicians & gurus, price momentum, valuation, analyst consensus, financial health, earnings momentum. The higher the score, the more favorable the institutional signals consensus.

💡 Detailed breakdown (the 8 sub-scores) available in the Premium dashboard.

About Upstream Bio, Inc.

Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases focusing on severe respiratory disorders. It offers verekitug, which is in Phase 2 trials for the treatment of severe asthma and chronic rhinosinusitis with nasal polyps and chronic obstructive pulmonary disease and in Phase I clinical trial for treating chronic obstructive pulmonary disease. The company was incorporated in 2021 and is headquartered in Waltham, Massachusetts.

Key info

👔
CEO
Dr. E. Rand Sutherland M.D., M.P.H.
📍
HQ
890 Winter Street, Suite 200, Waltham, MA, 02451, United States
👥
Employees
75
💰
Market cap
276 046 020,00 $US
💸
Dividend yield
—

🕴️ Insider activity (90 days)

5 transactions — 0 buys and 5 sales reported by Upstream Bio, Inc. executives.

DA
Deykin Aaron
Chief Medical Officer · 2026-09-16
Sell
SE
Sutherland Everett Rand
Chief Executive Officer · 2026-09-16
Sell
HA
Houghton Adam
Chief Business Officer · 2026-09-16
Sell

🏦 Hedge Funds

15 institutional funds report a position on UPB in their latest SEC quarterly filing.

VANGUARD GROUP INC
FMR LLC
NORGES BANK
BlackRock, Inc.
VANGUARD CAPITAL MANAGEMENT LLC

📰 Recent news

15 recent articles on UPB.

🧠 What makes Kairos Insider

Beyond raw data, we aggregate and score every smart money signal to give you a unique view.

🧠

Kairos Score 0-100

8-dimension composite score: insiders · hedge funds · politicians · momentum · valuation · health · analysts · earnings.

🎯

Insider Clusters

Detection of clustered purchases or sales by several executives in the same stock.

🏦

13F Hedge Funds

Berkshire, Pershing Square, Tiger Global, Bridgewater and other reporting funds.

📈

ETF Rotations

NANC & GOP (Pelosi & Republicans), GURU (top hedge funds), ARK (Cathie Wood). See who enters and exits each week.

🔥

Google Trends

Spot marked changes in search interest around the stocks being followed.

📧

Email alerts

Create your watchlist and receive a brief of events affecting your tickers.

Companies in the same sector as Upstream Bio, Inc.

Official sources · Public data · SEC EDGAR — Form 4 & 13F · AMF — Executive filings · BaFin — Directors' Dealings · Yahoo Finance · Alpha Vantage

🔓 Unlock the full analysis

This public page only shows a preview. The full analysis of UPB on the Kairos Insider dashboard includes:

✅ Full Kairos Score (8-axis radar + synthesis)
✅ History of all 5 insider transactions over 90 days
✅ All 15 detected institutional funds
✅ Thematic ETFs (ARK, BUZZ, NANC, GOP, JEPI…)
✅ Hot Stocks Google Trends
✅ Available history: AUM + rotations
✅ Fundamentals (P/E, PEG, EV/EBITDA, ROE…)
✅ Financial health (Altman Z, Piotroski F)
✅ Sector peers + recent earnings
See full analysis →
Analyze other tickers for free →

Free signup · Pro €19/month or €190/year